Production Scale Fermenter

Production Scale Fermenter

Available in 500 ltr to 20000 Ltr variants.

Total Capacities

500-20000Liters

Working Volume

Variable

Design:

Designed as per ASME standards

to comply with the required

pressure in vessels and in

Bioprocess.

Type:

SS316L vessel with glass window

and SS304 jacket, In-situ Sterilizable

(SIP & CIP)

Controls:

Auto temperature/RPM:20-2800/

pH/DO2 with cascade control/

Antifoam/Air flow/auto

sterilization through Modular

Micro-controller & PID Controls.

Other probes for out-gases etc

available on demand.

Drive:

Top driven and direct coupled Motor

with single/double mechanical seal.

Steam/Air

filtration

0.22 µm PTFE filter Cartridge with

SS316L housing plus 0.45/0.22µm

prefilter with SS housing.

Control Panel:

Multi colored PLC/TFT Touch

Screen/Graphic display Control

panel with HMI for

monitoring and control of pH/Temp/

DO2 and Agitation.

D/H Ratio

1:2.5 Automatic control for Temperature,

Sterilization, Agitation, Aeration pH DO,

Pressure, Antifoam, Acid, Base, Feed,

MFC etc.

Vessel and Jacket

Design Parameters

Max. Working Temp for vessel:150

deg C and for Jacket: 140deg C

Working Pressure for vessel: 3.0 Bar

and for Jacket: 3.75 Bar Design

Temp. for vessel will be 150

deg and for Jacket 150 deg C

Design Pressure for vessel will

be 3.0 Bar and for

jacket 4.0 Bar

Provision of Ports

On the top plate with safety

valve, agitator, gas outlet,

light glass, pressure

gauges, additional

ports with a collar,

air sparger, air by pass, 3 nos. of

standard ports for acid, Alkali

and feed. At 1/3 height of shell/vessel

from bottom provided with 25 mm

standard ports for pH ,DO ,temperature

probes and a sampling valve in the

bottom dish, Jacket -provided with

ports for steam/water entry,

standard ports, Jacket drain etc.

Agitator Assembly

Shaft, 3/4 nos. of Ruston turbine

impellers, single/double mechanical

seal. Motor & RPM are customized as

per requirement. Accuracy 1 RPM

with VFD/Speed controller card etc.

Top Plate

Bolted to the shell. Bottom shell

welded to the shell, jacket cover

80% of the total height, All parts

in contact with culture made of

SS 316 L, Jacket and spiral – SS

304 , “O” rings made of EDPM,

silicone

Pipe Line Fittings

and Accessories

Inlet/outlet cartridge filters with

SS316L housing and pressure

gauges,. meter for flow

measurement etc

Steam/Water

Connection

With diaphragm control valves

to control sterilization temperature

, All the valves in the lines connected

to the jacket are pneumatically

operated from the control panel.

Base frame

Suitable base frame. MOC:

SS304 to house the vessel,

agitator assembly along with

pipe rack etc.